Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 13/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889812 | 0.79 | ALOX5 (0.63) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL20889279 | 0.79 | ALOX5 (0.63) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL20889539 | 0.79 | ALOX5 (0.63) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL7963701 | 0.76 | GAA (0.71) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL20889493 | 0.72 | ALOX5 (0.63) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL1970735 | 0.71 | GAA (0.52) | GAAMAPTALDH1A1LMNAHTT | |
| SCHEMBL14022531 | 0.71 | GAA (0.65) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL20889534 | 0.70 | TRIM24 (0.59) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL31355246 | 0.70 | GAA (0.83) | GAAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL13790187 | 0.69 | BRAF (0.69) | GAAMAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027119-A2 | SUBSTANCE LIBRARY CONTAINING BICYCLIC IMIDAZO-5-YL-AMINES AND/OR BICYCLIC IMIDAZO-3-YL-AMINES | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | claimed |
| WO-2001027119-A2 | SUBSTANCE LIBRARY CONTAINING BICYCLIC IMIDAZO-5-YL-AMINES AND/OR BICYCLIC IMIDAZO-3-YL-AMINES | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | disclosed |