Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.55 |
| ▸ | KDM5A | P29375 | 4/20 | 0.55 |
| ▸ | KDM5C | P41229 | 4/20 | 0.55 |
| ▸ | KDM6B | O15054 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13383551 | 0.94 | KDM4E (0.69) | KDM4EKDM5BKDM5AKDM5CKDM6B | |
| SCHEMBL14291398 | 0.92 | KDM4E (0.52) | KDM4EKDM5BKDM5AKDM5CKDM6B | |
| SCHEMBL2877274 | 0.91 | KDM5B (0.67) | KDM4EKDM5BKDM5AKDM5CKDM6B | |
| SCHEMBL13702267 | 0.88 | ACACB (0.57) | KDM4EKDM5BKDM5AKDM5CKDM1A | |
| SCHEMBL28590470 | 0.87 | JMJD6 (0.66) | KDM4EKDM5BKDM5AKDM5CSMYD2 | |
| SCHEMBL9792819 | 0.86 | KDM4E (0.64) | KDM4EKDM5BKDM5AKDM5CKDM6B | |
| SCHEMBL13702392 | 0.85 | ABL1 (0.53) | KDM4EKDM5BKDM5AKDM5CKDM1A | |
| SCHEMBL4353042 | 0.84 | ITGB3 (0.47) | KDM4EKDM5BKDM5AKDM5CKDM6B | |
| SCHEMBL12061585 | 0.84 | KDM5A (0.47) | KDM4EKDM5BKDM5AKDM5CKDM1A | |
| SCHEMBL13702255 | 0.84 | CYP2A6 (0.52) | KDM1AHDAC1CDK8HDAC6RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6087510-A | Method of use of imidazolium cations | THE ROCKEFELLER UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |