⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1073213 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL11218093 | 0.73 | HSD17B10 (0.33) | — | |
| SCHEMBL17254181 | 0.70 | — | — | |
| SCHEMBL534990 | 0.69 | — | — | |
| SCHEMBL27611845 | 0.69 | — | — | |
| SCHEMBL1698070 | 0.69 | — | — | |
| SCHEMBL1430229 | 0.69 | — | — | |
| SCHEMBL14479633 | 0.68 | — | — | |
| Iodide SCHEMBL2430931 | 0.68 | CHRNB2 (0.48) | — | |
| SCHEMBL11292475 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670432-A | Pyrazolopyridine derivatives useful in treating inflammation and allergic conditions | BEECHAM GROUP P.L.C. (GB) | 1987-06-02 | — | — | US | claimed |
| EP-0152910-A2 | pyrazolopyridine derivatives | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | claimed |
| US-6218380-B1 | USEFUL FOR EFFECTING .BETA.-LATAMASE INHIBITION IN HUMANS AND ANIMALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-04-17 | — | — | US | disclosed |