SCHEMBL7963907

SCHEMBL7963907

CN(C)C(=O)C1=C(C(=O)Nc2ccc(Cl)c(C=CC(=O)OCCCl)c2)CCCC1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 8/20 0.38
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
GAA P10253 1/20 0.38
DHODH Q02127 1/20 0.37
RCE1 Q9Y256 1/20 0.37
APEX1 P27695 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ACHE P22303 3/20 0.36
MAOB P27338 2/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
GSTO1 P78417 1/20 0.35
HPGD P15428 1/20 0.35
PTBP1 P26599 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8637532 0.87 NPSR1 (0.40) NPSR1MAPTALDH1A1KDM4EGAA
SCHEMBL7963906 0.79 NPSR1 (0.38) NPSR1MAPTKDM4EDHODHAPEX1
SCHEMBL7767725 0.77 KMT2A (0.39) NPSR1MAPTALDH1A1KDM4EDHODH
SCHEMBL11246084 0.74 GRM4 (0.56) NPSR1MAPTALDH1A1KDM4EDHODH
SCHEMBL11242017 0.72 GRM4 (0.43) NPSR1MAPTALDH1A1KDM4EGAA
SCHEMBL7963909 0.72 KMT2A (0.42) NPSR1MAPTALDH1A1KDM4EGAA
SCHEMBL11241892 0.71 TSHR (0.53) NPSR1MAPTALDH1A1DHODHMEN1
SCHEMBL8304677 0.65 NPSR1 (0.50) NPSR1DHODHKMT2ALMNA
SCHEMBL4682700 0.65 MAPT (0.46) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL4682697 0.65 MAPT (0.46) MAPTALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204222-B1 SUITABLE AS HERBICIDES AND FOR DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-20 US disclosed