Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244655 | 0.82 | NAMPT (0.44) | TSHRNPSR1MAPTALDH1A1LMNA | |
| SCHEMBL7693974 | 0.81 | SLC6A3 (0.60) | NPSR1SMN1; SMN2MAPTDHODHRAB9A | |
| SCHEMBL11246084 | 0.80 | GRM4 (0.56) | NPSR1SMN1; SMN2MAPTHSD17B10DHODH | |
| SCHEMBL7194464 | 0.80 | NPSR1 (0.54) | TSHRNPSR1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL11241747 | 0.79 | KMT2A (0.48) | TSHRNPSR1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL30913585 | 0.78 | DHODH (0.69) | NPSR1SMN1; SMN2MAPTDHODHRAB9A | |
| SCHEMBL11242017 | 0.74 | GRM4 (0.43) | TSHRNPSR1SMN1; SMN2MAPTDHODH | |
| SCHEMBL3915672 | 0.71 | DHODH (0.60) | NPSR1SMN1; SMN2MAPTDHODHALDH1A1 | |
| SCHEMBL20129481 | 0.71 | DHODH (0.51) | NPSR1SMN1; SMN2MAPTDHODHRAB9A | |
| SCHEMBL10408176 | 0.70 | NPSR1 (0.47) | NPSR1SMN1; SMN2MAPTDHODHRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55157546-A | — | — | None | — | — | JP | disclosed |
| US-4362546-A | Tetrahydrophthalamide derivatives, herbicidal compositions and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-12-07 | — | — | US | disclosed |
| JP-S55157546-A | TETRAHYDROPHTHALAMIDE DERIVATIVE, ITS PREPARATION AND HERBICIDE | TAKEDA CHEM IND LTD | 1980-12-08 | — | — | JP | disclosed |