Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246084 | 0.83 | GRM4 (0.56) | GRM4HDAC6NPSR1KDM4EMEN1 | |
| SCHEMBL11256040 | 0.78 | SLC6A3 (0.46) | GRM4HDAC6NPSR1MEN1ALDH1A1 | |
| SCHEMBL11241892 | 0.74 | TSHR (0.53) | NPSR1MEN1ALDH1A1KMT2ADHODH | |
| SCHEMBL7963909 | 0.73 | KMT2A (0.42) | NPSR1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7767725 | 0.72 | KMT2A (0.39) | NPSR1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7963907 | 0.72 | NPSR1 (0.38) | NPSR1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7963906 | 0.72 | NPSR1 (0.38) | GRM4HDAC6NPSR1KDM4EMEN1 | |
| SCHEMBL11249257 | 0.70 | GRM4 (0.42) | GRM4NPSR1KDM4EMEN1ALDH1A1 | |
| SCHEMBL4125735 | 0.65 | TDP1 (0.56) | MEN1ALDH1A1KMT2APOLBNPC1 | |
| SCHEMBL2522639 | 0.64 | KDM4E (0.47) | KDM4EMEN1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362546-A | Tetrahydrophthalamide derivatives, herbicidal compositions and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-12-07 | — | — | US | disclosed |