Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | PRCP | P42785 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | CCR2 | P41597 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957652 | 0.87 | DRD2 (0.55) | DRD2MCHR1PRCPDRD3ADRA1A | |
| SCHEMBL7961237 | 0.87 | PRCP (0.52) | DRD2MCHR1PRCPDRD3POLB | |
| SCHEMBL7960163 | 0.87 | DRD2 (0.62) | DRD2MCHR1PRCPDRD3CCR2 | |
| SCHEMBL7949642 | 0.84 | DRD2 (0.59) | DRD2CCR2OPRM1KMT2APOLB | |
| SCHEMBL7963815 | 0.83 | DRD2 (0.50) | DRD2MCHR1PRCPDRD3CCR2 | |
| SCHEMBL7964065 | 0.83 | DRD2 (0.53) | DRD2MCHR1PRCPDRD3CCR2 | |
| SCHEMBL7961377 | 0.81 | DRD2 (0.58) | DRD2PRCPHTR1AHTR2AKMT2A | |
| SCHEMBL7963985 | 0.81 | DRD2 (0.52) | DRD2HTR1ADRD3CCR2HTR2A | |
| SCHEMBL8001944 | 0.80 | DRD2 (0.65) | DRD2HTR1ADRD3CCR2HTR2A | |
| SCHEMBL8011291 | 0.80 | DRD2 (0.65) | DRD2HTR1ADRD3CCR2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |