Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957652 | 0.87 | DRD2 (0.55) | PRCPDRD2LMNAPOLBHTT | |
| SCHEMBL7960163 | 0.87 | DRD2 (0.62) | PRCPDRD2DRD4DRD3MCHR1 | |
| SCHEMBL7963986 | 0.87 | DRD2 (0.62) | PRCPDRD2POLBHTTDRD3 | |
| SCHEMBL7949642 | 0.84 | DRD2 (0.59) | DRD2POLBHTTSIGMAR1CYP2J2 | |
| SCHEMBL7961236 | 0.81 | CCR2 (0.46) | PRCPDRD2 | |
| SCHEMBL7961377 | 0.81 | DRD2 (0.58) | PRCPDRD2HTTDRD4SIGMAR1 | |
| SCHEMBL7963815 | 0.79 | DRD2 (0.50) | PRCPDRD2DRD4DRD3MCHR1 | |
| SCHEMBL7964065 | 0.79 | DRD2 (0.53) | PRCPDRD2DRD4DRD3MCHR1 | |
| SCHEMBL28442559 | 0.79 | SIGMAR1 (0.66) | PRCPDRD2LMNAPOLBHTT | |
| SCHEMBL7949583 | 0.78 | DRD2 (0.54) | PRCPDRD2POLBDRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |