Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.51 |
| ▸ | PTGIR | P43119 | 4/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949263 | 0.84 | PTGER4 (0.58) | RXRARXRBPTGER4PTGIRPTGER3 | |
| SCHEMBL7479094 | 0.83 | PTGIR (0.73) | RXRARXRBPTGER4PTGIRPTGER3 | |
| SCHEMBL9006885 | 0.83 | PTGIR (0.73) | RXRARXRBPTGER4PTGIRPTGER3 | |
| SCHEMBL7949957 | 0.83 | PTGIR (0.73) | RXRARXRBPTGER4PTGIRPTGER3 | |
| SCHEMBL7959999 | 0.82 | PTGER4 (0.70) | RXRARXRBPTGER4PTGIRPTGER3 | |
| SCHEMBL7490131 | 0.80 | PTGIR (0.69) | RXRARXRBPTGER4PTGIRPTGER3 | |
| SCHEMBL7495199 | 0.79 | PTGIR (0.68) | RXRARXRBPTGER4PTGIRPTGER3 | |
| SCHEMBL7495210 | 0.79 | PTGIR (0.68) | RXRARXRBPTGER4PTGIRPTGER3 | |
| SCHEMBL7480950 | 0.78 | PTGIR (0.65) | RXRARXRBPTGER4PTGIRPTGER3 | |
| SCHEMBL7489516 | 0.77 | PTGER4 (0.56) | RXRARXRBPTGER4PTGIRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0989975-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998055468-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |