Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANTXR2 | P58335 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805313 | 0.77 | MAPT (0.50) | ANTXR2MAOAMEN1KMT2AGLA | |
| SCHEMBL9149137 | 0.74 | MEN1 (0.48) | ANTXR2MAOAMEN1KMT2AGLA | |
| SCHEMBL11790033 | 0.74 | ANTXR2 (0.47) | ANTXR2MAOAMEN1KMT2AGLA | |
| SCHEMBL28016321 | 0.74 | ANTXR2 (0.47) | ANTXR2MAOAMEN1KMT2AGLA | |
| SCHEMBL11791101 | 0.72 | ANTXR2 (0.46) | ANTXR2MAOAMEN1KMT2AGLA | |
| Hydrochloric Acid SCHEMBL5207145 | 0.71 | CA12 (0.43) | ANTXR2MAOAMEN1KMT2AL3MBTL1 | |
| SCHEMBL10429703 | 0.71 | KMT2A (0.58) | ANTXR2MEN1KMT2ACYP3A4L3MBTL1 | |
| SCHEMBL1308058 | 0.71 | KMT2A (0.59) | MEN1KMT2ACYP3A4L3MBTL1ELANE | |
| SCHEMBL11794883 | 0.71 | MEN1 (0.44) | ANTXR2MAOAMEN1KMT2AGLA | |
| SCHEMBL9461565 | 0.71 | KMT2A (0.51) | ANTXR2MEN1KMT2ACYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1215835-C | Ketone derivatives and medical use thereof | TORAY INDUSTRIES (JP) | 2005-08-24 | — | — | CN | disclosed |
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| CN-1194580-A | Ketone derivatives and medical use thereof | TORAY INDUSTRIES (JP) | 1998-09-30 | — | — | CN | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |