SCHEMBL805313

SCHEMBL805313

Cc1cc(O)c(C)c(=O)o1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
CYP3A4 P08684 2/20 0.50
ANTXR2 P58335 1/20 0.50
TP53 P04637 1/20 0.50
MAOA P21397 1/20 0.48
MEN1 O00255 7/20 0.46
KMT2A Q03164 7/20 0.46
GLA P06280 1/20 0.46
KDM4E B2RXH2 2/20 0.45
MAPK1 P28482 2/20 0.45
ELANE P08246 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
NQO1 P15559 1/20 0.44
MCL1 Q07820 1/20 0.44
POLB P06746 1/20 0.42
HSD17B3 P37058 1/20 0.42
ALDH1A1 P00352 4/20 0.41
GAA P10253 3/20 0.41
ALOX12 P18054 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7964266 0.77 ANTXR2 (0.47) MAPTCYP3A4ANTXR2TP53MAOA
SCHEMBL11790033 0.77 ANTXR2 (0.47) MAPTCYP3A4ANTXR2MAOAMEN1
SCHEMBL28016321 0.77 ANTXR2 (0.47) MAPTCYP3A4ANTXR2TP53MAOA
SCHEMBL9149137 0.77 MEN1 (0.48) MAPTCYP3A4ANTXR2MAOAMEN1
SCHEMBL16432832 0.76 KDM4E (0.41) MAPTCYP3A4ANTXR2TP53MAOA
SCHEMBL11791101 0.76 ANTXR2 (0.46) MAPTCYP3A4ANTXR2TP53MAOA
SCHEMBL8507929 0.75 NQO1 (0.48) MAPTCYP3A4ANTXR2TP53MAOA
SCHEMBL1308058 0.74 KMT2A (0.59) MAPTCYP3A4MEN1KMT2AKDM4E
SCHEMBL9461565 0.74 KMT2A (0.51) MAPTCYP3A4ANTXR2MEN1KMT2A
SCHEMBL800045 0.74 MAPT (0.54) MAPTCYP3A4ANTXR2MAOAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008702-A1 CATALYST FOR DECOMPOSING ORGANIC MATTER AND SYSTEM FOR DECOMPOSING ORGANIC MATTER COMPRISING THE SAME UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR) 2026-01-08 US disclosed
US-11897793-B2 Catalysts for Fenton system containing metal oxide containing functional group on surface and Fenton system using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2024-02-13 US disclosed
CN-113441125-B Catalyst for Fenton reaction system comprising metal oxide having functional group on surface and Fenton reaction system using same 韩国科学技术研究院 2023-11-24 CN disclosed
CN-112795617-B Marine fungus secondary metabolite and preparation and application thereof 海南大学 2023-07-07 CN disclosed
US-20220127255-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (GB) 2022-04-28 US disclosed
CN-112795617-A Marine fungus secondary metabolite and preparation and application thereof 海南大学 2021-05-14 CN disclosed
US-20170157111-A1 HIF INHIBITORS AND USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2017-06-08 US disclosed
US-9604958-B2 HIF inhibitors and use thereof THE GENERAL HOSPITAL CORPORATION (US) 2017-03-28 US disclosed
US-20150023868-A1 HIF INHIBITORS AND USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2015-01-22 US disclosed
EP-2429993-B1 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION BOEHRINGER INGELHEIM INT (DE) 2015-01-21 EP disclosed
US-20120070369-A1 HIF INHIBITORS AND USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2012-03-22 US disclosed
WO-2010068794-A2 HIF INHIBITORS AND USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2010-06-17 WO disclosed
US-20070111952-A1 Glycosylated triketide delta lactones UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127255-A1 HERBICIDAL COMPOUNDS DDT, HDHD5, HPD MAPT 3573/4885CYP3A4 672/4885ANTXR2 2417/4885
US-20120070369-A1 HIF INHIBITORS AND USE THEREOF HIF1AN, HIF1A, EGLN3 MAPT 4004/4885CYP3A4 4195/4885ANTXR2 1573/4885
US-20070111952-A1 Glycosylated triketide delta lactones AGL, AKR1C3, AKR1C4 MAPT 4801/4885CYP3A4 305/4885ANTXR2 638/4885
US-20260008702-A1 CATALYST FOR DECOMPOSING ORGANIC MATTER AND SYSTEM FOR DECOMPOSING ORGANIC MATTER COMPRISING THE SAME HAO2, AOC3, OR10J3 MAPT 2440/4885CYP3A4 44/4885ANTXR2 2772/4885
US-20150023868-A1 HIF INHIBITORS AND USE THEREOF HIF1AN, HIF1A, EGLN3 MAPT 4004/4885CYP3A4 4195/4885ANTXR2 1573/4885
US-20170157111-A1 HIF INHIBITORS AND USE THEREOF HIF1AN, HIF1A, EGLN3 MAPT 4004/4885CYP3A4 4195/4885ANTXR2 1573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.