SCHEMBL7964342

SCHEMBL7964342

COc1ccc(C(C)C(=O)NC2(C(=O)O)CCC(C(C)(C)C)CC2)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 3/20 0.38
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SMYD3 Q9H7B4 1/20 0.34
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
HPGDS O60760 1/20 0.32
PTGS2 P35354 3/20 0.32
PTGS1 P23219 2/20 0.32
AKR1C3 P42330 2/20 0.32
AKR1C2 P52895 2/20 0.32
CDC42 P60953 1/20 0.32
RAC1 P63000 1/20 0.32
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7957825 0.92 ALDH1A1 (0.35) CXCR5ALDH1A1MEN1CYP2C9CYP2C19
SCHEMBL7950122 0.89 CXCR5 (0.39) CXCR5ALDH1A1MEN1KMT2ASMYD3
SCHEMBL7961986 0.88 CXCR5 (0.41) CXCR5SMYD3PTGS2PTGS1AKR1C3
SCHEMBL7958362 0.88 CXCR5 (0.39) CXCR5ALDH1A1SMYD3PTGS2PTGS1
SCHEMBL7958053 0.86 CXCR5 (0.41) CXCR5ALDH1A1MEN1CYP2C9KMT2A
SCHEMBL7958019 0.86 MEN1 (0.39) CXCR5MEN1KMT2ASMYD3MAPT
SCHEMBL7960124 0.85 CXCR5 (0.41) CXCR5MEN1CYP2C9KMT2A
SCHEMBL7949626 0.85 CXCR5 (0.41) CXCR5MEN1CYP2C9KMT2A
SCHEMBL7960778 0.85 CXCR5 (0.41) CXCR5MEN1CYP2C9KMT2A
SCHEMBL7960096 0.84 ALDH1A1 (0.42) ALDH1A1MEN1CYP2C9CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172255-B1 INSECTICIDES; MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-5830826-A Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides BAYER AKTIENGESELLSCHAFT (DE) 1998-11-03 US disclosed