Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | CDC42 | P60953 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960983 | 0.91 | KMT2A (0.42) | ALDH1A1KMT2ANPSR1MEN1CYP2C19 | |
| SCHEMBL6474821 | 0.88 | NPSR1 (0.40) | ALDH1A1KMT2ANPSR1MEN1CYP2C19 | |
| SCHEMBL7961955 | 0.87 | GPR88 (0.44) | KMT2AMEN1GPR88GAASMYD3 | |
| SCHEMBL7960746 | 0.87 | GPR88 (0.44) | ALDH1A1KMT2AMEN1CYP2C19GPR88 | |
| SCHEMBL7949841 | 0.86 | GPR88 (0.44) | ALDH1A1KMT2AMEN1CYP2C19GPR88 | |
| SCHEMBL8652414 | 0.86 | P2RX7 (0.39) | ALDH1A1CYP2C19CYP2C9GAACYP3A4 | |
| SCHEMBL8698327 | 0.84 | GPR88 (0.48) | KMT2AMEN1GPR88GAAPTGS2 | |
| SCHEMBL7960895 | 0.84 | GPR88 (0.45) | KMT2AMEN1GPR88GAASMYD3 | |
| SCHEMBL7964342 | 0.84 | CXCR5 (0.38) | ALDH1A1KMT2ANPSR1MEN1CYP2C19 | |
| SCHEMBL8701623 | 0.83 | GPR88 (0.47) | KMT2AMEN1GPR88GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |