Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906344 | 0.92 | GAA (0.34) | MAPTLMNAHPGDL3MBTL1KMT2A | |
| SCHEMBL7960620 | 0.92 | NPC1 (0.36) | NPC1RAB9AMAPTLMNAHPGD | |
| SCHEMBL7960414 | 0.86 | ALDH1A1 (0.36) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL8796492 | 0.85 | NPC1 (0.37) | NPC1RAB9AMAPTLMNAHPGD | |
| SCHEMBL7961784 | 0.81 | MAPT (0.36) | MAPTL3MBTL1LPAR1ALDH1A1 | |
| SCHEMBL8905461 | 0.81 | GAA (0.36) | LMNAHPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL8906967 | 0.81 | L3MBTL1 (0.40) | NPC1RAB9ALMNAHPGDKDM4E | |
| SCHEMBL7960239 | 0.80 | MAPT (0.38) | NPC1RAB9AMAPTKDM4EL3MBTL1 | |
| SCHEMBL7960902 | 0.80 | MAPT (0.38) | NPC1RAB9AMAPTKDM4EL3MBTL1 | |
| SCHEMBL7949834 | 0.80 | MAPT (0.38) | NPC1RAB9AMAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |