⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312968 | 0.74 | — | — | |
| SCHEMBL11325094 | 0.74 | — | — | |
| SCHEMBL11326049 | 0.69 | LMNA (0.30) | — | |
| SCHEMBL9328970 | 0.56 | — | — | |
| SCHEMBL5870791 | 0.54 | — | — | |
| SCHEMBL144898 | 0.53 | — | — | |
| SCHEMBL3195818 | 0.53 | — | — | |
| SCHEMBL10637978 | 0.52 | — | — | |
| SCHEMBL11139354 | 0.45 | CYP3A4 (0.42) | — | |
| SCHEMBL51843 | 0.42 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242437-B1 | HAS HIGHER ANTIMICROBIAL ACTIVITY AGAINST METHICILLINE-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA), PENICILLIN-RESISTANT STREPTOCOCCUS PNEUMONIAE (PRSP), AND IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA ONIUM SALT | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0947517-A1 | CEPHEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |