Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489241 | 1.00 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| Trimethylammonium SCHEMBL27503278 | 0.94 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| Trimethylammonium SCHEMBL27504350 | 0.94 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL28224352 | 0.90 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL8098946 | 0.88 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL31682199 | 0.84 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL24604163 | 0.82 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL7174445 | 0.82 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL6862330 | 0.82 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL2637137 | 0.82 | KDM4E (0.56) | SLC6A2SLC6A4SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820204-A | Preparation method of R-3-benzyl-3-piperidine formyl trimethylhydrazine | 山东百诺医药股份有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-116354870-A | Method for synthesizing 3-benzyl-1- (tert-butoxycarbonyl) piperidine-3-carboxylic acid | 苏州特瑞药业股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-116354870-B | Method for synthesizing 3-benzyl-1- (tert-butoxycarbonyl) piperidine-3-carboxylic acid | 苏州特瑞药业股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-117820204-A | Preparation method of R-3-benzyl-3-piperidine formyl trimethylhydrazine | 山东百诺医药股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116354870-A | Method for synthesizing 3-benzyl-1- (tert-butoxycarbonyl) piperidine-3-carboxylic acid | 苏州特瑞药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-102584937-B | (3R) crystal form of 1 (2 methylalanyl-d D tryptophanyl) 3 (benzyl) 3 piperidine carboxylic acid 1,2,2 trimethylhydrazide | 赫尔辛医疗股份公司 | 2017-03-01 | — | — | CN | disclosed |
| EP-1871765-B1 | 3-(INDAZOL-5-YL)-(1,2,4)TRIAZINE DERIVATIVES AND RELATED COMPOUNDS AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | SCHERING CORP (US) | 2009-12-09 | — | — | EP | disclosed |
| EP-1096926-A2 | METHODS AND COMPOUNDS FOR TREATING DEPRESSION | NPS PHARMACEUTICALS, INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002551-A2 | METHODS AND COMPOUNDS FOR TREATING DEPRESSION | NPS PHARMACEUTICALS, INC. (US) | 2000-01-20 | — | — | WO | disclosed |
| US-5929243-A | STEREOSPECIFIC HYDROLYSIS OF AN N-PROTECTED ETHYL ESTER OF 2-BENZYL-2-CARBETHOXY-3-AMINO PROPIONIATE USING AN ESTERASE AND OBTAINING AN OPTICAL STEREOISOMER OF THE CORRESPONDING MONO-ACID; DEPROTECTING; CYCLIZATION; CHEMICAL REDUCTION | MERCK & CO., INC. (US) | 1999-07-27 | — | — | US | disclosed |