Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489241 | 0.88 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL7964628 | 0.88 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| Trimethylammonium SCHEMBL27503278 | 0.83 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| Trimethylammonium SCHEMBL27504350 | 0.83 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL31682199 | 0.82 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL2637137 | 0.80 | KDM4E (0.56) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL31682187 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6MEN1 | |
| SCHEMBL6862330 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL8407276 | 0.80 | KDM4E (0.56) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7174445 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719772-B1 | OPTICALLY ACTIVE IMIDAZOLIDINONE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5726188-A | TREATING SENILE DEMENTIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0719772-A1 | OPTICALLY ACTIVE IMIDAZOLIDINONE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |