Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933092 | 0.80 | KDM4E (0.56) | SLC2A1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL7965141 | 0.77 | SLC2A1 (0.54) | SLC2A1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL18509726 | 0.73 | SLC2A1 (0.55) | SLC2A1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL18029380 | 0.72 | SLC2A1 (0.49) | SLC2A1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL31370393 | 0.72 | SLC2A1 (0.49) | SLC2A1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL8293138 | 0.70 | ADRA2A (0.47) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7693001 | 0.69 | AKR1C2 (0.49) | SLC2A1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL24723412 | 0.68 | MEN1 (0.58) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9017471 | 0.68 | AKR1C2 (0.47) | SLC2A1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL25748034 | 0.67 | HTR2C (0.66) | SLC2A1ALDH1A1KDM4EMAPTABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252084-B1 | THERAPY FOR SEPSIS SHOCK | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |