⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964619 | 0.86 | — | — | |
| SCHEMBL7492128 | 0.85 | SETDB1 (0.31) | — | |
| SCHEMBL7963870 | 0.65 | CHEK1 (0.31) | — | |
| SCHEMBL7492830 | 0.63 | — | — | |
| SCHEMBL5656919 | 0.56 | SMN1; SMN2 (0.58) | — | |
| SCHEMBL7968349 | 0.56 | TP53 (0.34) | — | |
| SCHEMBL5652939 | 0.55 | CYP1A2 (0.58) | — | |
| SCHEMBL5632849 | 0.54 | MEN1 (0.55) | — | |
| SCHEMBL29287051 | 0.54 | ATM (0.38) | — | |
| SCHEMBL229506 | 0.51 | CA12 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242437-B1 | HAS HIGHER ANTIMICROBIAL ACTIVITY AGAINST METHICILLINE-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA), PENICILLIN-RESISTANT STREPTOCOCCUS PNEUMONIAE (PRSP), AND IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA ONIUM SALT | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0947517-A1 | CEPHEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |