SCHEMBL229506

SCHEMBL229506

O=S(=O)(O)NCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.68
CA2 P00918 4/20 0.68
CA7 P43166 3/20 0.68
CA14 Q9ULX7 3/20 0.68
CA1 P00915 4/20 0.64
KEAP1 Q14145 1/20 0.61
CA9 Q16790 2/20 0.53
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
THRB P10828 1/20 0.50
IDO1 P14902 1/20 0.50
LMNA P02545 1/20 0.50
KMT2A Q03164 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HTT P42858 1/20 0.50
KDM4E B2RXH2 1/20 0.49
POLB P06746 1/20 0.49
TSHR P16473 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10953887 0.98 CA12 (0.65) CA12CA2CA7CA14CA1
Ammonia Solution, Strong SCHEMBL4593139 0.98 CA12 (0.65) CA12CA2CA7CA14CA1
Water SCHEMBL3952740 0.98 CA12 (0.65) CA12CA2CA7CA14CA1
Benzyl(Benzylsulfamoyl)Amine SCHEMBL2298224 0.81 CA12 (1.00) CA12CA2CA7CA14CA1
Sulfuric Acid SCHEMBL9523482 0.79 CA2 (0.61) CA12CA2CA7CA14CA1
Sulfuric Acid SCHEMBL9523490 0.79 CA2 (0.61) CA12CA2CA7CA14CA1
SCHEMBL5653047 0.78 CA9 (0.54) CA12CA2CA7CA14CA1
SCHEMBL20534987 0.78 CA12 (0.51) CA12CA2CA7CA14CA1
SCHEMBL22690487 0.78 CA2 (0.56) CA12CA2CA7CA14CA1
SCHEMBL5656919 0.78 SMN1; SMN2 (0.58) CA2L3MBTL1LMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 829 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230147312-A1 TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND RELATED CONDITIONS WITH ANTAGONISTS OF E-SELECTIN GLYCOMIMETICS, INC. (US) 2023-05-11 US claimed
US-20230113110-A1 COMPOSITION FOR THE TREATMENT OF LESIONS OF THE RESPIRATORY SYSTEM BARRITAULT DENIS (FR) 2023-04-13 US claimed
EP-4117781-A1 COMPOSITION FOR THE TREATMENT OF LESIONS OF THE RESPIRATORY SYSTEM Organes Tissus Régénération Réparation Remplacement (FR) 2023-01-18 EP claimed
CN-115209954-A Composition for treating respiratory disorders 生物组织再生和修复公司 2022-10-18 CN claimed
US-20220220144-A1 MULTIMERIC PAN-SELECTIN ANTAGONISTS GLYCOMIMETICS, INC. (US) 2022-07-14 US claimed
US-20220152089-A1 COMPOSITION FOR THE PROTECTION AND REPAIR OF THE BLOOD BRAIN BARRIER Organes Tissus Regeneration, Reparation, Remplacement (FR) 2022-05-19 US claimed
CN-114206354-A Compositions for the protection and repair of the Blood Brain Barrier (BBB) 生物组织再生和修复公司 2022-03-18 CN claimed
EP-3914225-A1 COSMETIC/DERMATOLOGICAL COMPOSITION Organes Tissus Régénération Réparation Remplacement (FR) 2021-12-01 EP claimed
CN-113473963-A Cosmetic/dermatological composition 生物组织再生和修复公司 2021-10-01 CN claimed
WO-2021195465-A1 TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND RELATED CONDITIONS WITH ANTAGONISTS OF E-SELECTIN MAGNANI JOHN L (US) 2021-09-30 WO claimed
US-4786721-A DYEING OR PRINTING CELLULOSE FIBERS CIBA-GEIGY CORPORATION (US) 1988-11-22 US claimed
US-4766206-A Reactive dyestuffs comprising a vinylsulfonylalkylaminocarbonyl moiety CIBA-GEIGY CORPORATION (US) 1988-08-23 US claimed
US-4746732-A COTTON AND WOOL CIBA-GEIGY CORPORATION (US) 1988-05-24 US claimed
EP-0134192-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-09-30 EP claimed
US-4342869-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-08-03 US claimed
US-4338437-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-07-06 US claimed
US-4338438-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-07-06 US claimed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US claimed
US-4297488-A 7-α-Methoxy cephalosporins MERCK & CO., INC. (US) 1981-10-27 US claimed
US-4092308-A 4-Sulphomethyl substituted hydroxypyridone azo dyestuffs CIBA-GEIGY CORPORATION (US) 1978-05-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220152089-A1 COMPOSITION FOR THE PROTECTION AND REPAIR OF THE BLOOD BRAIN BARRIER FABP7, PGF, VEGFA CA12 1331/4885CA2 1213/4885CA7 1415/4885
US-20230113110-A1 COMPOSITION FOR THE TREATMENT OF LESIONS OF THE RESPIRATORY SYSTEM PRDX5, LCT, MPO CA12 617/4885CA2 436/4885CA7 554/4885
US-20220220144-A1 MULTIMERIC PAN-SELECTIN ANTAGONISTS SELE, SELP, BSG CA12 796/4885CA2 2559/4885CA7 2308/4885
US-20230147312-A1 TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND RELATED CONDITIONS WITH ANTAGONISTS OF E-SELECTIN SELP, SELE, SELPLG CA12 1554/4885CA2 3911/4885CA7 4114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.