Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.66 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768135 | 1.00 | ITGB3 (0.66) | ITGB3ITGA2BCPB2CTSKTSHR | |
| SCHEMBL4917735 | 0.96 | ITGB3 (0.61) | ITGB3ITGA2BCPB2CTSKTSHR | |
| SCHEMBL6384973 | 0.85 | ITGB3 (0.58) | ITGB3ITGA2BCTSKTSHRTGM2 | |
| SCHEMBL6384976 | 0.85 | ITGB3 (0.58) | ITGB3ITGA2BCTSKTSHRTGM2 | |
| SCHEMBL6386152 | 0.84 | ITGB3 (0.63) | ITGB3ITGA2BTSHRHDAC4HDAC1 | |
| SCHEMBL10074274 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BTSHRTGM2 | |
| SCHEMBL6824202 | 0.84 | ITGB3 (0.63) | ITGB3ITGA2BTSHRHDAC4HDAC1 | |
| SCHEMBL4906556 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BTSHRTGM2 | |
| SCHEMBL6386159 | 0.84 | ITGB3 (0.63) | ITGB3ITGA2BTSHRHDAC4HDAC1 | |
| SCHEMBL6824212 | 0.84 | ITGB3 (0.63) | ITGB3ITGA2BTSHRHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079792-C | DP-IV-serine protease inhibitors | FERRING BV (NL) | 2002-02-27 | — | — | CN | disclosed |
| US-6201132-B1 | INHIBITORS OF MEMBRANE-BOUND SERINE PROTEASE; AMINOACYL COMPOUNDS | FERRING B.V. (NL) | 2001-03-13 | — | — | US | disclosed |