Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.55 |
| ▸ | DPP4 | P27487 | 3/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.55 |
| ▸ | PREP | P48147 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906556 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL4913602 | 0.97 | DPP7 (0.54) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL4913612 | 0.88 | PREP (0.50) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL6890952 | 0.86 | PREP (0.48) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL6100308 | 0.85 | PREP (0.52) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL7964692 | 0.84 | ITGB3 (0.66) | ITGB3ITGA2BTGM2TSHR | |
| SCHEMBL6768135 | 0.84 | ITGB3 (0.66) | ITGB3ITGA2BTGM2TSHR | |
| SCHEMBL6100302 | 0.84 | PREP (0.53) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL5351068 | 0.83 | PREP (0.57) | ITGB3ITGA2BDPP7DPP4DPP8 | |
| SCHEMBL27586353 | 0.83 | PREP (0.57) | ITGB3ITGA2BDPP7DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |