SCHEMBL7964787

SCHEMBL7964787

CCCCC(=O)OC1(C)C2CC3CC(C2)CC1C3

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.46
CYP19A1 P11511 2/20 0.46
EPHX2 P34913 8/20 0.40
NPSR1 Q6W5P4 1/20 0.36
NAAA Q02083 2/20 0.36
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12197282 0.91 CYP17A1 (0.49) CYP17A1CYP19A1EPHX2ALDH1A1
SCHEMBL6744513 0.83 CYP17A1 (0.43) CYP17A1CYP19A1EPHX2
SCHEMBL119734 0.82 CYP19A1 (0.50) CYP17A1CYP19A1ALDH1A1
SCHEMBL15041028 0.81 CYP17A1 (0.42) CYP17A1CYP19A1EPHX2TP53
SCHEMBL13527839 0.81 CYP17A1 (0.47) CYP17A1CYP19A1
SCHEMBL16121051 0.80 CES2 (0.42) CYP17A1CYP19A1EPHX2TP53
SCHEMBL14871543 0.79 CES2 (0.45) CYP17A1CYP19A1EPHX2TP53
SCHEMBL11948969 0.79 CYP17A1 (0.39) CYP17A1CYP19A1EPHX2
SCHEMBL17322536 0.79 CYP19A1 (0.50) CYP17A1CYP19A1
SCHEMBL13588098 0.79 CYP17A1 (0.45) CYP17A1CYP19A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6280897-B1 GENERATION OF ACID WITH ACTINIC RADIATION KABUSHIKI KAISHA TOSHIBA (JP) 2001-08-28 US disclosed