Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207191 | 0.80 | HDAC1 (0.60) | HDAC1HDAC2HDAC3NPC1MAPT | |
| SCHEMBL30832967 | 0.80 | HDAC1 (0.60) | HDAC1HDAC2HDAC3NPC1MAPT | |
| SCHEMBL12845563 | 0.79 | HDAC1 (0.44) | HDAC1NPC1MAPTRAB9APOLB | |
| SCHEMBL8110762 | 0.78 | HDAC2 (0.83) | HDAC1HDAC2HDAC3NPC1MAPT | |
| SCHEMBL1708819 | 0.78 | HDAC1 (0.62) | HDAC1HDAC2HDAC3NPC1MAPT | |
| SCHEMBL28177918 | 0.78 | PRKCI (0.38) | HDAC1HDAC2HDAC3NPC1MAPT | |
| SCHEMBL2610988 | 0.77 | MAPT (0.62) | HDAC1NPC1MAPTRAB9APOLB | |
| SCHEMBL10372226 | 0.77 | HDAC1 (0.60) | HDAC1HDAC2HDAC3NPC1MAPT | |
| SCHEMBL11512570 | 0.77 | HDAC1 (0.60) | HDAC1HDAC2HDAC3NPC1MAPT | |
| SCHEMBL11678263 | 0.76 | HDAC1 (0.46) | HDAC1HDAC2HDAC3NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017272-A2 | METHOD OF TREATING NEUROLOGICAL DISEASES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-02-11 | — | — | WO | disclosed |