Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964853 | 1.00 | DRD4 (0.44) | DRD4KCNA3CTSKOPRM1OPRD1 | |
| SCHEMBL1808105 | 0.79 | CTSK (0.61) | KCNA3CTSKOPRM1OPRD1OPRK1 | |
| SCHEMBL1699916 | 0.79 | CTSK (0.61) | KCNA3CTSKOPRM1OPRD1OPRK1 | |
| SCHEMBL1699915 | 0.79 | CTSK (0.61) | KCNA3CTSKOPRM1OPRD1OPRK1 | |
| SCHEMBL7956176 | 0.77 | CTSK (0.50) | KCNA3CTSKOPRM1OPRD1OPRK1 | |
| SCHEMBL6959302 | 0.77 | CTSK (0.50) | KCNA3CTSKOPRM1OPRD1OPRK1 | |
| SCHEMBL6959306 | 0.77 | CTSK (0.50) | KCNA3CTSKOPRM1OPRD1OPRK1 | |
| SCHEMBL803320 | 0.77 | CTSK (0.58) | CTSKOPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL3440554 | 0.75 | CTSK (0.56) | CTSKOPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL3104685 | 0.74 | CTSK (0.58) | CTSKOPRM1OPRD1OPRK1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255315-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | disclosed |