Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.38 |
| ▸ | TUBB | P07437 | 3/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954361 | 0.90 | L3MBTL1 (0.45) | L3MBTL1GAAKMT2ARAB9ATUBB4A | |
| SCHEMBL7418271 | 0.84 | KMT2A (0.47) | GAAKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7430332 | 0.83 | MAPT (0.46) | L3MBTL1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7424234 | 0.82 | MAPT (0.47) | GAAKMT2AALDH1A1MAPTTSHR | |
| SCHEMBL7425788 | 0.77 | KDM4E (0.54) | L3MBTL1GAAKMT2ARAB9AALDH1A1 | |
| SCHEMBL7593381 | 0.77 | BRD4 (0.43) | L3MBTL1GAAKMT2ARAB9AMAPT | |
| Hydrochloric Acid SCHEMBL7598923 | 0.76 | BRD4 (0.42) | L3MBTL1GAAKMT2ARAB9AMAPT | |
| SCHEMBL7427541 | 0.74 | BCL2L1 (0.35) | L3MBTL1GAAKMT2ANPC1ALDH1A1 | |
| SCHEMBL7423134 | 0.74 | PTPN1 (0.51) | L3MBTL1GAAKMT2AALDH1A1MAPT | |
| SCHEMBL7427546 | 0.74 | TUBB4A (0.42) | L3MBTL1GAAKMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |