Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969553 | 0.92 | L3MBTL1 (0.55) | KMT2ADRD4PRMT5WDR77L3MBTL1 | |
| SCHEMBL7953572 | 0.90 | KMT2A (0.54) | KMT2AMAPTMAPK1PRMT5WDR77 | |
| SCHEMBL7953344 | 0.90 | KDM4E (0.53) | KMT2ACACNA1GDRD4MAPTMAPK1 | |
| SCHEMBL7969310 | 0.90 | L3MBTL1 (0.51) | KMT2ADRD4PRMT5WDR77L3MBTL1 | |
| SCHEMBL7966950 | 0.90 | TSHR (0.56) | KMT2AMAPTPRMT5WDR77L3MBTL1 | |
| SCHEMBL7953454 | 0.90 | PRMT5 (0.47) | PRMT5WDR77L3MBTL1SMN1; SMN2ABCB1 | |
| SCHEMBL7200720 | 0.90 | SMN1; SMN2 (0.57) | MAPTMAPK1PRMT5WDR77SMN1; SMN2 | |
| SCHEMBL27193282 | 0.90 | SMN1; SMN2 (0.57) | MAPTMAPK1PRMT5WDR77SMN1; SMN2 | |
| SCHEMBL7966384 | 0.89 | MAPT (0.53) | KMT2AMAPTMAPK1PRMT5WDR77 | |
| SCHEMBL7964392 | 0.88 | CYP1A2 (0.58) | KMT2AMAPTSMN1; SMN2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |