Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | F8 | P00451 | 1/20 | 0.45 |
| ▸ | F5 | P12259 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965174 | 0.88 | KMT2A (0.52) | KMT2AABCB1MAPTSMN1; SMN2 | |
| SCHEMBL7965117 | 0.87 | CYP1A2 (0.58) | CYP1A2CYP2D6MEN1USP2HTT | |
| SCHEMBL7963819 | 0.85 | MAOA (0.46) | MAPTTP53 | |
| SCHEMBL7953962 | 0.84 | ABCB1 (0.54) | CYP1A2CYP2D6MEN1USP2HTT | |
| SCHEMBL7964394 | 0.84 | OPRL1 (0.43) | CYP1A2CYP2D6 | |
| SCHEMBL8019951 | 0.84 | MEN1 (0.49) | MEN1HTTKMT2ANPSR1ABCB1 | |
| SCHEMBL7969553 | 0.83 | L3MBTL1 (0.55) | CYP2D6MEN1KMT2AABCB1SMN1; SMN2 | |
| SCHEMBL7953297 | 0.83 | LMNA (0.55) | MEN1KMT2ANPSR1ABCB1MAPT | |
| SCHEMBL7964386 | 0.83 | LMNA (0.39) | CYP1A2CYP2D6USP2KMT2ANPSR1 | |
| SCHEMBL7200720 | 0.82 | SMN1; SMN2 (0.57) | USP2HTTNPSR1ABCB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |