SCHEMBL7965196

SCHEMBL7965196

CCCCCCCCCCCC(=O)c1c[nH]c(C(=O)OC)c1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BAZ2B Q9UIF8 1/20 0.68
BAZ2A Q9UIF9 1/20 0.68
ALDH1A1 P00352 5/20 0.59
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
BRD4 O60885 1/20 0.46
HSD17B3 P37058 6/20 0.45
PTPN2 P17706 2/20 0.42
PTPN1 P18031 2/20 0.42
CDC25B P30305 2/20 0.42
HTT P42858 1/20 0.41
FFAR1 O14842 1/20 0.41
PLA2G2A P14555 1/20 0.41
PLA2G5 P39877 1/20 0.41
STS P08842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9151585 1.00 BAZ2B (0.68) BAZ2BBAZ2AALDH1A1LMNAGAA
SCHEMBL9147964 1.00 BAZ2B (0.68) BAZ2BBAZ2AALDH1A1LMNAGAA
SCHEMBL29191043 0.88 BAZ2B (0.77) BAZ2BBAZ2AALDH1A1LMNAGAA
SCHEMBL9517009 0.87 BAZ2B (0.51) BAZ2BBAZ2AALDH1A1LMNAHSD17B3
SCHEMBL5858863 0.87 BAZ2B (0.51) BAZ2BBAZ2AALDH1A1LMNAHSD17B3
SCHEMBL5859454 0.87 BAZ2B (0.51) BAZ2BBAZ2AALDH1A1LMNAHSD17B3
SCHEMBL5858212 0.86 BAZ2B (0.52) BAZ2BBAZ2AALDH1A1LMNABRD4
SCHEMBL12704136 0.84 TDP1 (0.56) BAZ2BBAZ2AALDH1A1GAABRD4
SCHEMBL9150472 0.79 LMNA (0.48) BAZ2BBAZ2AALDH1A1LMNAHSD17B3
SCHEMBL9150821 0.79 LMNA (0.48) BAZ2BBAZ2AALDH1A1LMNAHSD17B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310217-B1 ANTIINFLAMMATORY AND ANALGESIC AGENTS MERCKLE GMBH (DE) 2001-10-30 US disclosed
US-RE35096-E Antilipemic, anticholesterol, arteriosclerosis MITSUBISHI CHEMICAL CORPORATION (JP) 1995-11-21 US disclosed
EP-0434070-B1 Pyrrolealdehyde derivative MITSUBISHI CHEM CORP (JP) 1995-08-09 EP disclosed
US-5153217-A Antiiipemic, anticholesterol agents MITSUBISHI KASEI CORPORATION (JP) 1992-10-06 US disclosed
US-5082856-A Hyperlipemia, arteriosclerosis MITSUBISHI KASEI CORPORATION (JP) 1992-01-21 US disclosed
EP-0434070-A2 Pyrrolealdehyde derivative Mitsubishi Chemical Corporation (JP) 1991-06-26 EP disclosed
EP-0347902-A2 Pyrrolecarboxylic acid derivatives Mitsubishi Chemical Corporation (JP) 1989-12-27 EP disclosed