Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150821 | 1.00 | LMNA (0.48) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9517009 | 0.89 | BAZ2B (0.51) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL5859454 | 0.89 | BAZ2B (0.51) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL5858863 | 0.89 | BAZ2B (0.51) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL5858212 | 0.87 | BAZ2B (0.52) | LMNAMAPK1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL2518047 | 0.80 | BAZ2B (0.56) | LMNASMN1; SMN2ALDH1A1MAPTBAZ2B | |
| SCHEMBL6198697 | 0.80 | BAZ2B (0.49) | LMNAALDH1A1BAZ2BBAZ2AESR1 | |
| SCHEMBL9151585 | 0.79 | BAZ2B (0.68) | LMNAALDH1A1HTTBAZ2BBAZ2A | |
| SCHEMBL9147964 | 0.79 | BAZ2B (0.68) | LMNAALDH1A1HTTBAZ2BBAZ2A | |
| SCHEMBL7965196 | 0.79 | BAZ2B (0.68) | LMNAALDH1A1HTTBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35096-E | Antilipemic, anticholesterol, arteriosclerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |
| US-5082856-A | Hyperlipemia, arteriosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0347902-A2 | Pyrrolecarboxylic acid derivatives | Mitsubishi Chemical Corporation (JP) | 1989-12-27 | — | — | EP | disclosed |