Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855817 | 0.86 | KCNA5 (0.48) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL14564600 | 0.80 | TSHR (0.44) | LMNAPOLBTSHRNPC1RAB9A | |
| SCHEMBL7328664 | 0.80 | HPGD (0.45) | LMNAPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL7391934 | 0.79 | NPC1 (0.49) | LMNAPOLBALDH1A1TSHRNPC1 | |
| SCHEMBL6232571 | 0.79 | RIPK1 (0.50) | CTSSCTSKPTPN1LMNAPOLB | |
| SCHEMBL1573222 | 0.78 | ITGA4 (0.54) | ALDH1A1NPC1RAB9AMEN1GAA | |
| SCHEMBL3180198 | 0.77 | ATM (0.53) | CTSSCTSKALDH1A1NPC1RAB9A | |
| SCHEMBL21960819 | 0.76 | KCNA5 (0.56) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL4632779 | 0.75 | CA12 (0.60) | CTSSCTSKLMNACTSLCTSB | |
| SCHEMBL6443449 | 0.75 | EPHX2 (0.49) | CTSSCTSKCTSLCTSBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214826-B1 | NERVOUS SYSTEM DISORDERS | ZENECA LIMITED (GB) | 2001-04-10 | — | — | US | disclosed |