Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6176614 | 0.90 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL6175357 | 0.86 | CCKBR (0.42) | CCKBRNPY1RRAB9ACCKAR | |
| SCHEMBL7951149 | 0.83 | CCKBR (0.46) | CCKBRNPY1RRAB9ACCKAR | |
| SCHEMBL6177837 | 0.81 | CCKBR (0.54) | CCKBRNPY1RRAB9A | |
| SCHEMBL6177012 | 0.80 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL6179058 | 0.79 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL6175491 | 0.79 | CYP3A4 (0.46) | CCKBRNPY1RRAB9A | |
| SCHEMBL6178645 | 0.79 | CCKBR (0.45) | CCKBRNPY1RRAB9A | |
| Hydrochloric Acid SCHEMBL6178483 | 0.78 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL6178211 | 0.78 | CCKBR (0.52) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |