Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180327 | 0.89 | TSHR (0.41) | CCKBRALDH1A1TSHRNPSR1GFER | |
| SCHEMBL6181436 | 0.88 | CCKBR (0.41) | CCKBRALDH1A1TSHRNPSR1GFER | |
| SCHEMBL7965347 | 0.86 | CCKBR (0.41) | CCKBRNPY1RRAB9ACCKAR | |
| SCHEMBL6176809 | 0.84 | PREP (0.44) | TSHRNPSR1GFERPREPKDM4E | |
| SCHEMBL7951149 | 0.82 | CCKBR (0.46) | CCKBRNPY1RRAB9ACCKAR | |
| SCHEMBL6180195 | 0.80 | PREP (0.49) | ALDH1A1TSHRNPSR1GFERPREP | |
| SCHEMBL6177837 | 0.80 | CCKBR (0.54) | CCKBRNPY1RRAB9A | |
| SCHEMBL6177012 | 0.79 | CCKBR (0.49) | CCKBRLMNACCKAR | |
| SCHEMBL6178645 | 0.79 | CCKBR (0.45) | CCKBRNPY1RRAB9A | |
| Hydrochloric Acid SCHEMBL7960986 | 0.78 | CCKBR (0.44) | CCKBRNPY1RRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |