Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462454 | 0.78 | TSHR (0.39) | OPRM1TSHRDNM1 | |
| SCHEMBL19988007 | 0.78 | — | — | |
| SCHEMBL15827071 | 0.77 | — | — | |
| SCHEMBL1343853 | 0.77 | — | — | |
| SCHEMBL16501370 | 0.77 | — | — | |
| SCHEMBL4566710 | 0.77 | OPRM1 (0.46) | OPRM1PLA2G1BPLA2G2ASLC1A3SLC1A2 | |
| SCHEMBL1960950 | 0.75 | ALDH1A1 (0.45) | OPRM1TSHRALDH1A1TDP1 | |
| SCHEMBL21900733 | 0.75 | ALDH1A1 (0.45) | OPRM1TSHRALDH1A1TDP1 | |
| SCHEMBL18948037 | 0.75 | OPRM1 (0.52) | OPRM1TSHRPLA2G1BPLA2G2ASLC1A3 | |
| SCHEMBL8021589 | 0.75 | OPRM1 (0.52) | OPRM1TSHRPLA2G1BPLA2G2ASLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177437-B1 | VIRICIDES | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER | 2001-01-23 | — | — | US | disclosed |