Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | PTGES | O14684 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953327 | 0.84 | GAA (0.38) | CA9PTGESHSD17B10ALDH1A1MAPT | |
| SCHEMBL7965644 | 0.79 | CA9 (0.49) | CA12CA9PTGESALDH1A1MAPT | |
| SCHEMBL15233112 | 0.77 | CA9 (0.47) | CA12CA9PTGESBRD4BRPF1 | |
| SCHEMBL5633583 | 0.74 | CA9 (0.47) | CA12CA9HSD17B10ALDH1A1MAPT | |
| SCHEMBL7968737 | 0.72 | POLB (0.39) | CA12CA9HSD17B10ALDH1A1MAPT | |
| SCHEMBL10663908 | 0.69 | CA9 (0.50) | CA12CA9PTGESALDH1A1MAPT | |
| SCHEMBL13403281 | 0.69 | CYP1A2 (0.39) | CA12CA9BRD4BRPF1CREBBP | |
| SCHEMBL10750624 | 0.67 | HSD17B10 (0.38) | PTGESBRD4BRPF1EP300CREBBP | |
| SCHEMBL13893459 | 0.66 | PTGES (0.54) | PTGESHSD17B10MAPTPOLBKDM4E | |
| SCHEMBL16901820 | 0.64 | ELANE (0.49) | CA12CA9HSD17B10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |