Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15233112 | 0.85 | CA9 (0.47) | CA9CA12MITFLMNAMAPT | |
| SCHEMBL5633583 | 0.82 | CA9 (0.47) | CA9CA12MITFLMNAMAPT | |
| SCHEMBL10663908 | 0.80 | CA9 (0.50) | CA9CA12MAPTGAAALDH1A1 | |
| SCHEMBL7965502 | 0.79 | CA12 (0.42) | CA9CA12MAPTPOLBGAA | |
| SCHEMBL13403281 | 0.76 | CYP1A2 (0.39) | CA9CA12MITFLMNAMAPT | |
| SCHEMBL11843818 | 0.73 | POLB (0.57) | CA9MITFLMNAMAPTHTT | |
| SCHEMBL6023652 | 0.69 | CYP3A4 (0.48) | CA9CA12LMNAPOLBALDH1A1 | |
| SCHEMBL7968690 | 0.67 | MEN1 (0.48) | CA9MITFLMNAMAPTHTT | |
| SCHEMBL1308058 | 0.67 | KMT2A (0.59) | LMNAMAPTHTTPOLBGAA | |
| SCHEMBL280169 | 0.66 | MAPT (0.50) | CA9CA12MITFLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |