Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.57 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796269 | 0.87 | APP (0.55) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13198323 | 0.85 | SMN1; SMN2 (0.54) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL796277 | 0.85 | MAPT (0.48) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2247388 | 0.81 | SMN1; SMN2 (1.00) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30504076 | 0.81 | SMN1; SMN2 (1.00) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22015459 | 0.78 | MAPT (0.51) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30466258 | 0.77 | KDM4E (0.69) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12470903 | 0.77 | KDM4E (0.69) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30714873 | 0.76 | KDM4E (0.74) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9293186 | 0.76 | KDM4E (0.74) | MAPTKDM4ENPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070374-A1 | Compounds for Non-Invasive Measurement of Aggregates of Amyloid Peptides | TECHNISCHE UNIVERSITAT MUNCHEN (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120070374-A1 | Compounds for Non-Invasive Measurement of Aggregates of Amyloid Peptides | TECHNISCHE UNIVERSITAT MUNCHEN (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070374-A1 | Compounds for Non-Invasive Measurement of Aggregates of Amyloid Peptides | IAPP, APP, HTT | MAPT 10/4885KDM4E 4716/4885NPC1 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.