Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974383 | 0.92 | SIGMAR1 (0.40) | EBPSIGMAR1BCHEARUBE2M | |
| SCHEMBL7967158 | 0.89 | BCHE (0.41) | EBPSIGMAR1BCHEUBE2MDCUN1D1 | |
| SCHEMBL7965705 | 0.89 | SIGMAR1 (0.45) | EBPSIGMAR1BCHEUBE2MDCUN1D1 | |
| SCHEMBL7968588 | 0.88 | EBP (0.43) | EBPSIGMAR1ARUBE2MDCUN1D1 | |
| SCHEMBL7971484 | 0.87 | EBP (0.40) | EBPSIGMAR1ARUBE2MDCUN1D1 | |
| SCHEMBL7956198 | 0.86 | EBP (0.40) | EBPSIGMAR1BCHEUBE2MDCUN1D1 | |
| SCHEMBL7971696 | 0.85 | EBP (0.39) | EBPSIGMAR1BCHEARUBE2M | |
| SCHEMBL7967041 | 0.85 | BCHE (0.39) | EBPSIGMAR1BCHEUBE2MDCUN1D1 | |
| SCHEMBL7966979 | 0.84 | SIGMAR1 (0.45) | EBPSIGMAR1BCHECYP3A4ABCB1 | |
| SCHEMBL7972289 | 0.84 | EBP (0.40) | EBPSIGMAR1BCHEUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265439-B1 | Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives | G.D. SEARLE & CO. | 2001-07-24 | — | — | US | disclosed |