SCHEMBL7965828

SCHEMBL7965828

CCc1cc(OCC=C(Cl)Cl)cc(Cl)c1OCCCNc1ccc(Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.35
POLB P06746 1/20 0.34
PNLIP P16233 2/20 0.33
F2 P00734 1/20 0.32
RHOC P08134 2/20 0.32
RHOA P61586 2/20 0.32
PPARG P37231 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
GAA P10253 1/20 0.32
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
PTPN1 P18031 1/20 0.31
P4HB P07237 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
RECQL P46063 1/20 0.31
SCN9A Q15858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977787 0.97 HTT (0.40) HTTL3MBTL1POLBPNLIPRHOC
SCHEMBL7979221 0.92 HTT (0.42) HTTL3MBTL1PNLIPF2RHOC
SCHEMBL7976320 0.91 HTT (0.40) HTTL3MBTL1POLBF2RHOC
SCHEMBL7965793 0.88 HTT (0.39) HTTL3MBTL1PNLIPRHOCRHOA
SCHEMBL7965926 0.87 HTT (0.39) HTTL3MBTL1POLBPPARGFNTA
SCHEMBL7979272 0.86 HTT (0.38) HTTF2RHOCRHOAPPARG
SCHEMBL7965830 0.85 NPC1 (0.46) HTTL3MBTL1RHOCRHOAALDH1A1
SCHEMBL7976269 0.83 HTT (0.40) HTTRHOCRHOAPPARGNPSR1
SCHEMBL7965701 0.83 HTT (0.37) HTTPNLIPRHOCRHOAPPARG
SCHEMBL7979372 0.82 HTT (0.39) HTTPPARGKDM4EALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed