SCHEMBL7965701

SCHEMBL7965701

Fc1cc(OCC=C(Cl)Cl)cc(Cl)c1OCCCCNc1ccc(Cl)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.37
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
RHOC P08134 2/20 0.31
RHOA P61586 2/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
STK17A Q9UEE5 2/20 0.31
STK17B O94768 1/20 0.31
AR P10275 1/20 0.31
KCNH2 Q12809 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
GAA P10253 1/20 0.31
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
FFAR1 O14842 1/20 0.30
PPARG P37231 1/20 0.30
PPARD Q03181 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7979272 0.97 HTT (0.38) HTTDRD2DRD4DRD3RHOC
SCHEMBL7982119 0.90 HTT (0.34) HTTRHOCRHOASIGMAR1
SCHEMBL7965854 0.86 HTT (0.35) HTTRHOCRHOASIGMAR1
SCHEMBL7977787 0.86 HTT (0.40) HTTRHOCRHOAFNTAFNTB
SCHEMBL7965926 0.85 HTT (0.39) HTTDRD2DRD4DRD3FNTA
SCHEMBL7965704 0.85 RHOC (0.42) RHOCRHOAMEN1KMT2ACYP1A2
SCHEMBL7976362 0.84 HTT (0.41) HTTDRD2DRD4DRD3RHOC
SCHEMBL8656345 0.84 PLAU (0.39) HTTDRD2DRD4DRD3MEN1
SCHEMBL7982244 0.83 RHOC (0.33) DRD2DRD4DRD3RHOCRHOA
SCHEMBL7965828 0.83 HTT (0.40) HTTRHOCRHOAFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed