SCHEMBL7979272

SCHEMBL7979272

Fc1cc(OCC=C(Cl)Cl)cc(Cl)c1OCCCNc1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.38
DRD2 P14416 2/20 0.34
DRD4 P21917 2/20 0.34
DRD3 P35462 2/20 0.34
RHOC P08134 3/20 0.32
RHOA P61586 3/20 0.32
PPARG P37231 1/20 0.32
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
STK17A Q9UEE5 1/20 0.31
AR P10275 1/20 0.31
KCNH2 Q12809 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
GAA P10253 1/20 0.31
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
RECQL P46063 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7965701 0.97 HTT (0.37) HTTDRD2DRD4DRD3RHOC
SCHEMBL7965854 0.89 HTT (0.35) HTTRHOCRHOASIGMAR1
SCHEMBL7965926 0.88 HTT (0.39) HTTDRD2DRD4DRD3PPARG
SCHEMBL7982119 0.86 HTT (0.34) HTTRHOCRHOASIGMAR1
SCHEMBL7965828 0.86 HTT (0.40) HTTRHOCRHOAPPARGFNTA
SCHEMBL7979275 0.84 RHOC (0.45) RHOCRHOAMEN1KMT2AALDH1A1
SCHEMBL8659785 0.84 PLAU (0.39) HTTDRD2DRD4DRD3PPARG
SCHEMBL7965903 0.83 TRPM5 (0.34) HTTDRD2DRD4DRD3MEN1
SCHEMBL7977787 0.83 HTT (0.40) HTTRHOCRHOAFNTAFNTB
SCHEMBL8408424 0.82 HTT (0.38) HTTRHOCRHOAPPARGSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed