Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969008 | 0.91 | TP53 (0.50) | RENTP53TSHREBPSIGMAR1 | |
| SCHEMBL3233084 | 0.77 | HRH4 (0.59) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7966471 | 0.77 | TP53 (0.51) | RENTP53TSHREBPSIGMAR1 | |
| SCHEMBL19026636 | 0.76 | TP53 (0.50) | RENTP53TSHREBPSIGMAR1 | |
| SCHEMBL10466226 | 0.74 | KCNH2 (0.53) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL2367040 | 0.73 | TP53 (0.47) | RENTP53TSHREBPSIGMAR1 | |
| SCHEMBL9130942 | 0.71 | HRH4 (0.66) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9407527 | 0.70 | TSHR (0.52) | TSHRANPEPERAP2 | |
| SCHEMBL8678455 | 0.70 | TSHR (0.55) | RENTP53TSHREBPSIGMAR1 | |
| SCHEMBL10667108 | 0.70 | TSHR (0.55) | RENTP53TSHREBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271385-B1 | FUNGICIDES (SUCH AS THOSE FOR USE IN FARMING AND HORTICULTURE). | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-1020441-A1 | N-HETEROCYCLIC METHYLPROPYLAMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND GERMICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-4708960-A | N-(arylpropyl)-azolylureas, and fungicides containing these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | disclosed |