Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965952 | 1.00 | P2RX7 (0.48) | P2RX7NSD2NAMPTADRB2ADRB1 | |
| SCHEMBL7979965 | 0.79 | NAMPT (0.45) | P2RX7NAMPT | |
| SCHEMBL8195687 | 0.74 | P2RX7 (0.35) | P2RX7NSD2HDAC3HDAC4HDAC1 | |
| SCHEMBL8195689 | 0.74 | P2RX7 (0.35) | P2RX7NSD2HDAC3HDAC4HDAC1 | |
| SCHEMBL11233631 | 0.70 | MAPT (0.48) | — | |
| SCHEMBL11157133 | 0.64 | NAMPT (0.49) | NAMPT | |
| SCHEMBL11157679 | 0.64 | NAMPT (0.57) | P2RX7NAMPT | |
| SCHEMBL8195691 | 0.62 | P2RX7 (0.45) | P2RX7NSD2HDAC3HDAC4HDAC1 | |
| SCHEMBL5340353 | 0.62 | P2RX7 (0.46) | P2RX7NSD2 | |
| SCHEMBL5341006 | 0.62 | NSD2 (0.45) | P2RX7NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |