Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979968 | 0.81 | ALDH1A1 (0.48) | NAMPTP2RX7TUBBHTTPOLB | |
| SCHEMBL7976375 | 0.80 | NAMPT (0.58) | NAMPTTUBBHTTALDH1A1 | |
| SCHEMBL8195019 | 0.80 | NAMPT (0.58) | NAMPTTUBBHTTALDH1A1 | |
| SCHEMBL7965952 | 0.79 | P2RX7 (0.48) | NAMPTP2RX7 | |
| SCHEMBL7965949 | 0.79 | P2RX7 (0.48) | NAMPTP2RX7 | |
| SCHEMBL19639350 | 0.64 | TUBB (0.60) | NAMPTTUBBHTTMEN1MAPT | |
| SCHEMBL12335073 | 0.64 | NAMPT (0.93) | NAMPTHTTALDH1A1 | |
| SCHEMBL12335097 | 0.63 | NAMPT (0.84) | NAMPT | |
| SCHEMBL161710 | 0.63 | NAMPT (0.84) | NAMPT | |
| SCHEMBL8220319 | 0.63 | LMNA (0.47) | NAMPTHTTPOLBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |