SCHEMBL7965979

SCHEMBL7965979

CNC(=O)[C@@H](Cc1ccccc1)NC(=O)C(Cl)C[C@H](N)Cc1ccc2ccccc2c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FCER2 P06734 5/20 0.61
MMP2 P08253 7/20 0.55
MMP9 P14780 6/20 0.55
MMP8 P22894 6/20 0.55
MME P08473 2/20 0.48
ACE P12821 2/20 0.48
CPA1 P15085 2/20 0.48
ACE2 Q9BYF1 2/20 0.48
PLAT P00750 1/20 0.48
MMP1 P03956 8/20 0.47
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
CTSS P25774 1/20 0.46
MMP3 P08254 4/20 0.46
PSMB1 P20618 1/20 0.46
PSMB5 P28074 1/20 0.46
PSMB2 P49721 1/20 0.46
MMP7 P09237 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6851903 0.76 FCER2 (1.00) FCER2MMP2MMP9MMP8MMP1
SCHEMBL8206981 0.75 FCER2 (0.60) FCER2MMP2MMP9MMP8MME
SCHEMBL5556662 0.74 MMP2 (0.81) FCER2MMP2MMP9MMP8MMP1
SCHEMBL5558806 0.74 MMP2 (0.81) FCER2MMP2MMP9MMP8MMP1
SCHEMBL5558802 0.74 MMP2 (0.81) FCER2MMP2MMP9MMP8MMP1
SCHEMBL5556655 0.74 MMP2 (0.81) FCER2MMP2MMP9MMP8MMP1
SCHEMBL762206 0.74 FCER2 (0.57) FCER2MMP2MMP9MMP8MME
SCHEMBL29898367 0.74 MME (0.67) FCER2MMEACECPA1ACE2
SCHEMBL6434826 0.74 MMP2 (0.73) FCER2MMP2MMP9MMP8MME
SCHEMBL7650106 0.73 FCER2 (0.59) FCER2MMP2MMP9MMP8MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6274584-B1 PEPTIDE DERIVATIVES; BIOAVAILABILITY; ENZYME RESISTANCE; MILK AND WOOL PRODUCTION NOVO NORDISK A/S (DK) 2001-08-14 US disclosed