Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818033 | 0.90 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL29387947 | 0.90 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL8460646 | 0.89 | HPGD (0.55) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL28879929 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL29875909 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL29875304 | 0.81 | KDM4E (0.54) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL27952677 | 0.81 | KDM4E (0.54) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL8718849 | 0.81 | NR4A1 (0.74) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL28879996 | 0.80 | PTPN1 (0.54) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL29875165 | 0.80 | PTPN1 (0.54) | ALDH1A1HPGDKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277964-B1 | MONOCLONAL ANTIBODY WHICH BINDS POLYCYCLIC AROMATIC COMPOUNDS SUCH AS PHENANTHRENE AND BENZO(A)PYRENE; SENSITIVE AND ACCURATE ENVIRONMENTAL AND EXHAUST GAS MONITORING | OSAKA GAS COMPANY LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |