Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 8/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620588 | 0.91 | BCHE (0.59) | DRD3HTR1ABCHEDRD2 | |
| SCHEMBL9256731 | 0.90 | BCHE (0.53) | DRD3CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11397482 | 0.87 | CHRM2 (0.56) | DRD3CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11402233 | 0.85 | CHRM2 (0.53) | DRD3CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11402230 | 0.85 | CHRM2 (0.53) | DRD3CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11402227 | 0.85 | CHRM2 (0.53) | DRD3CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL6619060 | 0.84 | MAOB (0.53) | DRD3CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11398024 | 0.84 | CHRM2 (0.52) | DRD3CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL6621857 | 0.83 | BCHE (0.57) | DRD3HTR1AMAPK1BCHEDRD2 | |
| SCHEMBL7976319 | 0.82 | KCNA3 (0.54) | DRD3DRD2KDM1AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |