Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6621857 | 0.93 | BCHE (0.57) | BCHEHTR7DRD3HRH1HTR1A | |
| SCHEMBL7966072 | 0.90 | DRD3 (0.56) | BCHEKCNH2HTR2ASLC6A3CHRM1 | |
| SCHEMBL6619060 | 0.83 | MAOB (0.53) | BCHEKCNH2HTR2AHTR7SLC6A3 | |
| SCHEMBL6620588 | 0.82 | BCHE (0.59) | BCHEDRD3HTR1A | |
| SCHEMBL11397482 | 0.78 | CHRM2 (0.56) | BCHEKCNH2HTR2ASLC6A3CHRM1 | |
| SCHEMBL9252180 | 0.77 | SLC6A3 (0.64) | BCHEKCNH2HTR2AHTR7SLC6A3 | |
| Hydrochloric Acid SCHEMBL9352882 | 0.77 | BCHE (0.64) | BCHEKCNH2HTR2ASLC6A3CHRM1 | |
| SCHEMBL9250065 | 0.77 | DRD2 (0.68) | CYP2D6DRD3CYP1A2CYP2C9ADRA1A | |
| Hydrochloric Acid SCHEMBL11201992 | 0.76 | P2RX7 (0.53) | BCHEKCNH2HTR2AHTR7SLC6A3 | |
| SCHEMBL11402233 | 0.76 | CHRM2 (0.53) | BCHEKCNH2HTR2ASLC6A3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |