Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 10/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11397482 | 0.91 | CHRM2 (0.56) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11402233 | 0.89 | CHRM2 (0.53) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11402227 | 0.89 | CHRM2 (0.53) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11402230 | 0.89 | CHRM2 (0.53) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL7966072 | 0.84 | DRD3 (0.56) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11400229 | 0.82 | CHRM2 (0.51) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL9669576 | 0.77 | HTR7 (0.56) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL10382955 | 0.77 | CYP2D6 (0.55) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL6620588 | 0.76 | BCHE (0.59) | HTR1ADRD3BCHEDRD2 | |
| SCHEMBL11395716 | 0.76 | HTR1A (0.65) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261990-A | N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |