Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 16/20 | 0.58 |
| ▸ | HRH1 | P35367 | 16/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979503 | 1.00 | HRH2 (0.58) | HRH2HRH1KDM4EHRH3DRD2 | |
| SCHEMBL7966022 | 0.89 | HRH2 (0.54) | HRH2HRH1KDM4EHRH3DRD2 | |
| SCHEMBL7966042 | 0.89 | HRH2 (0.54) | HRH2HRH1KDM4EHRH3DRD2 | |
| SCHEMBL7978391 | 0.85 | DRD3 (0.41) | HRH2HRH1KDM4E | |
| SCHEMBL7979532 | 0.85 | HRH2 (0.62) | HRH2HRH1KDM4EHRH3DRD2 | |
| SCHEMBL7979778 | 0.85 | HRH1 (0.61) | HRH2HRH1HRH3 | |
| SCHEMBL7248246 | 0.81 | HRH2 (0.76) | HRH2HRH1KDM4EHRH3 | |
| SCHEMBL7982418 | 0.81 | HRH3 (0.47) | HRH2HRH1HRH3 | |
| SCHEMBL7250883 | 0.79 | HRH2 (0.65) | HRH2HRH1KDM4EHRH3DRD2 | |
| SCHEMBL7244782 | 0.79 | HRH2 (0.65) | HRH2HRH1KDM4EHRH3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |